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p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP
Lack of functional SAP protein, due to gene deletion or mutation, is the cause of X-linked lymphoproliferative disease (XLP), characterized by functionally impaired T and NK cells and a high risk of lymphoma development. We have demonstrated earlier that SAP has a pro-apoptotic function in T and B c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3562301/ https://ncbi.nlm.nih.gov/pubmed/23165210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22810 |
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