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p53 contributes to T cell homeostasis through the induction of pro-apoptotic SAP

Lack of functional SAP protein, due to gene deletion or mutation, is the cause of X-linked lymphoproliferative disease (XLP), characterized by functionally impaired T and NK cells and a high risk of lymphoma development. We have demonstrated earlier that SAP has a pro-apoptotic function in T and B c...

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書誌詳細
主要な著者: Madapura, Harsha S., Salamon, Daniel, Wiman, Klas G., Lain, Sonia, Klein, George, Klein, Eva, Nagy, Noémi
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3562301/
https://ncbi.nlm.nih.gov/pubmed/23165210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22810
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