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Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies
Acrolein (Acr) is a ubiquitous environmental pollutant found in cigarette smoke and automobile exhaust. It can also be produced endogenously by oxidation of polyunsaturated fatty acids. The Acr-derived 1,N(2)-propanodeoxyguanosine (Acr-dG) adducts in DNA are mutagenic lesions that are potentially in...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3561715/ https://ncbi.nlm.nih.gov/pubmed/23126278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3004104 |
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