Detection of acrolein-derived cyclic DNA adducts in human cells by monoclonal antibodies

Acrolein (Acr) is a ubiquitous environmental pollutant found in cigarette smoke and automobile exhaust. It can also be produced endogenously by oxidation of polyunsaturated fatty acids. The Acr-derived 1,N(2)-propanodeoxyguanosine (Acr-dG) adducts in DNA are mutagenic lesions that are potentially in...

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Bibliographische Detailangaben
Hauptverfasser: Pan, Jishen, Awoyemi, Bisola, Xuan, Zhuoli, Vohra, Priya, Wang, Hsiang-Tsui, Dyba, Marcin, Greenspan, Emily, Fu, Ying, Creswell, Karen, Zhang, Lihua, Berry, Deborah, Tang, Moon-Shong, Chung, Fung-Lung
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3561715/
https://ncbi.nlm.nih.gov/pubmed/23126278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx3004104
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