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Renal Nerves Drive Interstitial Fibrogenesis in Obstructive Nephropathy

The signals that drive fibrogenesis after an initiating insult to the kidney are incompletely understood. Here, we report that renal nerve stimulation after ureteral obstruction is the primary profibrotic signal and that renal denervation prevents both fibrogenesis and the inflammatory cascade. Loca...

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Bibliografski detalji
Glavni autori: Kim, Jinu, Padanilam, Babu J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559485/
https://ncbi.nlm.nih.gov/pubmed/23264683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012070678
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