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Renal Nerves Drive Interstitial Fibrogenesis in Obstructive Nephropathy
The signals that drive fibrogenesis after an initiating insult to the kidney are incompletely understood. Here, we report that renal nerve stimulation after ureteral obstruction is the primary profibrotic signal and that renal denervation prevents both fibrogenesis and the inflammatory cascade. Loca...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3559485/ https://ncbi.nlm.nih.gov/pubmed/23264683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012070678 |
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