Sphingosine 1-Phosphate Receptor 1 (S1P(1)) Upregulation and Amelioration of Experimental Autoimmune Encephalomyelitis by an S1P(1) Antagonist

Sphingosine 1-phosphate receptor 1 (S1P(1)) is a G protein–coupled receptor that is critical for proper lymphocyte development and recirculation. Agonists to S1P(1) are currently in use clinically for the treatment of multiple sclerosis, and these drugs may act on both S1P(1) expressed on lymphocyte...

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Bibliografische gegevens
Hoofdauteurs: Cahalan, Stuart M., Gonzalez-Cabrera, Pedro J., Nguyen, Nhan, Guerrero, Miguel, Cisar, Elizabeth A. George, Leaf, Nora B., Brown, Steven J., Roberts, Edward, Rosen, Hugh
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2013
Onderwerpen:
Accelerated Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558813/
https://ncbi.nlm.nih.gov/pubmed/23204443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082958
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