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Belatacept and Sirolimus Prolong Nonhuman Primate Islet Allograft Survival: adverse consequences of concomitant alefacept therapy
Calcineurin inhibitors (CNI) and steroids are known to promote insulin resistance, and their avoidance after islet transplantation is preferred from a metabolic standpoint. Belatacept, a B7-specific mediator of costimulation blockade (CoB), is clinically indicated as a CNI alternative in renal trans...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558637/ https://ncbi.nlm.nih.gov/pubmed/23279640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04341.x |
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