A Novel Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival

The importance of CD40/CD154 costimulatory pathway blockade in immunosuppression strategies is well documented. Efforts are currently focused on monoclonal antibodies specific for CD40 because of thromboembolic complications associated with monoclonal antibodies directed towards CD154. Here we prese...

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Main Authors: Lowe, M, Badell, IR, Thompson, P, Martin, B, Leopardi, F, Strobert, E, Price, AA, Abdulkerim, HS, Wang, R, Iwakoshi, NN, Adams, AB, Kirk, AD, Larsen, CP, Reimann, KA
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410651/
https://ncbi.nlm.nih.gov/pubmed/22845909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04054.x
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