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Islet Xenotransplantation Using Gal-deficient Neonatal Donors Improves Engraftment and Function

Significant deficiencies in understanding of xenospecific immunity have impeded the success of preclinical trials in xenoislet transplantation. While galactose-α1,3-galactose, the gal epitope, has emerged as the principal target of rejection in pig-to-primate models of solid organ transplant, the im...

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Detalhes bibliográficos
Main Authors: Thompson, P, Badell, IR, Lowe, M, Cano, J, Song, M, Leopardi, F, Avila, J, Ruhil, R, Strobert, E, Korbutt, G, Rayat, G, Rajotte, R, Iwakoshi, N, Larsen, CP, Kirk, AD
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226931/
https://ncbi.nlm.nih.gov/pubmed/21883917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2011.03720.x
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