Belatacept and Sirolimus Prolong Nonhuman Primate Renal Allograft Survival without a Requirement for Memory T Cell Depletion

Belatacept is an inhibitor of CD28/B7 costimulation that is clinically indicated as a calcineurin inhibitor (CNI) alternative in combination with mycophenolate mofetil and steroids after renal transplantation. We sought to develop a clinically translatable, non-lymphocyte depleting, belatacept-based...

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Bibliografiske detaljer
Main Authors: Lo, Denise J, Anderson, Douglas J, Weaver, Timothy A, Leopardi, Frank, Song, Mingqing, Farris, Alton B, Strobert, Elizabeth A, Jenkins, Joe, Turgeon, Nicole A, Mehta, Aneesh K, Larsen, Christian P, Kirk, Allan D
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558532/
https://ncbi.nlm.nih.gov/pubmed/23311611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2012.04342.x
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