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Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging.
The deubiquitinating enzyme, USP14, found in association with the proteasome is essential in mediating ubiquitin trimming and in ensuring ubiquitin-homeostasis. As aging is accompanied by a significant decline in proteasomal proteolysis in primary human T lymphocytes, we evaluated the contributory r...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2013
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3558606/ https://ncbi.nlm.nih.gov/pubmed/23291607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2012.12.007 |
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