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Altered regulation of CXCR4 expression during aging contributes to increased CXCL12-dependent chemotactic migration of CD4(+) T cells

Chemokine-dependent migration of T lymphocytes assures recirculation of naïve T cells to secondary lymphoid organs, and tissue specific trafficking of memory-effector T cells. Previous studies carried out in rodents, have demonstrated age-associated modulation of the expression of chemokine receptor...

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Detalhes bibliográficos
Main Authors: Cané, Stefania, Ponnappan, Subramaniam, Ponnappan, Usha
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399962/
https://ncbi.nlm.nih.gov/pubmed/22568557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2012.00830.x
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