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Impairment of non-muscle myosin IIA in human CD4(+) T cells contributes to functional deficits in the elderly
Physiological aging imposes significant alterations in the repertoire of T cells and all associated functions. Although several studies have reported defects upon antigen-induced activation of T cells during aging, the molecular mechanisms that control T-cell receptor (TCR) downmodulation remain to...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3560422/ https://ncbi.nlm.nih.gov/pubmed/21983869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2011.41 |
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