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Sulfiredoxin redox-sensitive interaction with S100A4 and non-muscle myosin IIA regulates cancer cell motility

Sulfiredoxin (Srx) is a redox active protein that participates in the reduction of oxidized cysteine residues. Here we identify a novel function of Srx through its specific binding to S-glutathionylated S100A4 affecting its interaction with non-muscle myosin (NMIIA), thereby modulating the effect of...

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書目詳細資料
Main Authors: Bowers, Robert R., Manevich, Yefim, Townsend, Danyelle M., Tew, Kenneth D.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472422/
https://ncbi.nlm.nih.gov/pubmed/22934964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301006w
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