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Redox regulation of the proteasome in T lymphocytes during aging

Proteasome is a major cellular organelle responsible for the regulated turn-over of both normal and misfolded proteins. Recent reports from our laboratory have implicated lowered proteasomal chymotryptic activity to be responsible for decreased induction of the transcription factor NFκB in T lymphoc...

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Autors principals: Das, Rupali, Ponnappan, Subramaniam, Ponnappan, Usha
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1858653/
https://ncbi.nlm.nih.gov/pubmed/17275686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2006.11.020
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