MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) exhibits strong intrinsic and acquired drug resistance which is the main obstacle to chemotherapy. Overexpression of ATP binding cassette (ABC) proteins correlates with activation of mitogen activated protein kinase (MAPK) pathway in HCC. Here, we systemati...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Lin, Shibo, Hoffmann, Katrin, Xiao, Zhi, Jin, Nan, Galli, Uwe, Mohr, Elvira, Büchler, Markus W, Schemmer, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2013
विषय:
Primary Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558388/
https://ncbi.nlm.nih.gov/pubmed/23320839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-3
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन