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Involvement of the epidermal growth factor receptor in the modulation of multidrug resistance in human hepatocellular carcinoma cells in vitro

BACKGROUND: Hepatocellular carcinoma (HCC) is a molecular complex tumor with high intrinsic drug resistance. Recent evidence suggests an involvement of the tyrosine kinase pathway in the regulation of ATP-binding cassette protein (ABC-transport protein) mediated multidrug resistance in cancer cells....

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Detalhes bibliográficos
Main Authors: Hoffmann, Katrin, Xiao, Zhi, Franz, Clemens, Mohr, Elvira, Serba, Susanne, Büchler, Markus W, Schemmer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3228664/
https://ncbi.nlm.nih.gov/pubmed/22088142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-40
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