Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Neuroblastomas are tumors of peripheral sympathetic neurons and are the most common solid tumor in children. To determine the genetic basis for neuroblastoma we performed whole-genome sequencing (6 cases), exome sequencing (16 cases), genome-wide rearrangement analyses (32 cases), and targeted analy...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sausen, Mark, Leary, Rebecca J., Jones, Siân, Wu, Jian, Reynolds, C. Patrick, Liu, Xueyuan, Blackford, Amanda, Parmigiani, Giovanni, Diaz, Luis A., Papadopoulos, Nickolas, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Hogarty, Michael D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2012
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557959/
https://ncbi.nlm.nih.gov/pubmed/23202128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2493
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