Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Ovarian Clear Cell Carcinoma (OCCC) is an aggressive human cancer that is generally resistant to therapy. To explore the genetic origin of OCCC, we determined the exomic sequences of eight tumors after immunoaffinity purification of cancer cells. Through comparative analyses of normal cells from the...

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Main Authors: Jones, Siân, Wang, Tian-Li, Shih, Ie-Ming, Mao, Tsui-Lien, Nakayama, Kentaro, Roden, Richard, Glas, Ruth, Slamon, Dennis, Diaz, Luis A., Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Papadopoulos, Nickolas
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076894/
https://ncbi.nlm.nih.gov/pubmed/20826764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1196333
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