Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma

Ovarian Clear Cell Carcinoma (OCCC) is an aggressive human cancer that is generally resistant to therapy. To explore the genetic origin of OCCC, we determined the exomic sequences of eight tumors after immunoaffinity purification of cancer cells. Through comparative analyses of normal cells from the...

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Bibliografiske detaljer
Main Authors: Jones, Siân, Wang, Tian-Li, Shih, Ie-Ming, Mao, Tsui-Lien, Nakayama, Kentaro, Roden, Richard, Glas, Ruth, Slamon, Dennis, Diaz, Luis A., Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Papadopoulos, Nickolas
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076894/
https://ncbi.nlm.nih.gov/pubmed/20826764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1196333
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