Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types

Mutations in the chromatin remodeling gene ARID1A have recently been identified in the majority of ovarian clear cell carcinomas (OCCCs). To determine the prevalence of mutations in other tumor types, we evaluated 759 malignant neoplasms including those of the pancreas, breast, colon, stomach, lung,...

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Main Authors: Jones, Siân, Li, Meng, Parsons, D Williams, Zhang, Xiaosong, Wesseling, Jelle, Kristel, Petra, Schmidt, Marjanka K, Markowitz, Sanford, Yan, Hai, Bigner, Darell, Hruban, Ralph H, Eshleman, James R, Iacobuzio-Donahue, Christine A, Goggins, Michael, Maitra, Anirban, Malek, Sami N, Powell, Steve, Vogelstein, Bert, Kinzler, Kenneth W, Velculescu, Victor E, Papadopoulos, Nickolas
Format: Artigo
Jezik:Inglês
Izdano: Wiley Subscription Services, Inc., A Wiley Company 2012
Teme:
Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240719/
https://ncbi.nlm.nih.gov/pubmed/22009941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21633
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