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Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma

Neuroblastomas are tumors of peripheral sympathetic neurons and are the most common solid tumor in children. To determine the genetic basis for neuroblastoma we performed whole-genome sequencing (6 cases), exome sequencing (16 cases), genome-wide rearrangement analyses (32 cases), and targeted analy...

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Detalhes bibliográficos
Main Authors: Sausen, Mark, Leary, Rebecca J., Jones, Siân, Wu, Jian, Reynolds, C. Patrick, Liu, Xueyuan, Blackford, Amanda, Parmigiani, Giovanni, Diaz, Luis A., Papadopoulos, Nickolas, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E., Hogarty, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557959/
https://ncbi.nlm.nih.gov/pubmed/23202128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.2493
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