Somatic Mutations in the Chromatin Remodeling Gene ARID1A Occur in Several Tumor Types

Mutations in the chromatin remodeling gene ARID1A have recently been identified in the majority of ovarian clear cell carcinomas (OCCCs). To determine the prevalence of mutations in other tumor types, we evaluated 759 malignant neoplasms including those of the pancreas, breast, colon, stomach, lung,...

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Autores principales: Jones, Siân, Li, Meng, Parsons, D Williams, Zhang, Xiaosong, Wesseling, Jelle, Kristel, Petra, Schmidt, Marjanka K, Markowitz, Sanford, Yan, Hai, Bigner, Darell, Hruban, Ralph H, Eshleman, James R, Iacobuzio-Donahue, Christine A, Goggins, Michael, Maitra, Anirban, Malek, Sami N, Powell, Steve, Vogelstein, Bert, Kinzler, Kenneth W, Velculescu, Victor E, Papadopoulos, Nickolas
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3240719/
https://ncbi.nlm.nih.gov/pubmed/22009941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21633
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