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An integrated approach to the ligand binding specificity of Neisseria meningitidis M1 alanine aminopeptidase by fluorogenic substrate profiling, inhibitory studies and molecular modeling

Neisseria meningitides is a gram-negative diplococcus bacterium and is the main causative agent of meningitis and other meningococcal diseases. Alanine aminopeptidase from N. meningitides (NmAPN) belongs to the family of metallo-exopeptidase enzymes, which catalyze the removal of amino acids from th...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Węglarz-Tomczak, Ewelina, Poręba, Marcin, Byzia, Anna, Berlicki, Łukasz, Nocek, Bogusław, Mulligan, Rory, Joachimiak, Andrzej, Drąg, Marcin, Mucha, Artur
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557594/
https://ncbi.nlm.nih.gov/pubmed/23131591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2012.10.018
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