Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/β-Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair

In Parkinson's disease (PD), neurogenesis is impaired in the subventricular zone (SVZ) of postmortem human PD brains, in primate nonhuman and rodent models of PD. The vital role of Wingless-type MMTV integration site (Wnt)/β-catenin signaling in the modulation of neurogenesis, neuroprotection,...

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Hlavní autoři: L'Episcopo, Francesca, Tirolo, Cataldo, Testa, Nunzio, Caniglia, Salvatore, Morale, Maria C., Deleidi, Michela, Serapide, Maria F., Pluchino, Stefano, Marchetti, Bianca
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556384/
https://ncbi.nlm.nih.gov/pubmed/22323720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5259-11.2012
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