Plasticity of Subventricular Zone Neuroprogenitors in MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine) Mouse Model of Parkinson's Disease Involves Cross Talk between Inflammatory and Wnt/β-Catenin Signaling Pathways: Functional Consequences for Neuroprotection and Repair

In Parkinson's disease (PD), neurogenesis is impaired in the subventricular zone (SVZ) of postmortem human PD brains, in primate nonhuman and rodent models of PD. The vital role of Wingless-type MMTV integration site (Wnt)/β-catenin signaling in the modulation of neurogenesis, neuroprotection,...

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Main Authors: L'Episcopo, Francesca, Tirolo, Cataldo, Testa, Nunzio, Caniglia, Salvatore, Morale, Maria C., Deleidi, Michela, Serapide, Maria F., Pluchino, Stefano, Marchetti, Bianca
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556384/
https://ncbi.nlm.nih.gov/pubmed/22323720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5259-11.2012
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