Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain

Neuroinflammatory processes are recognized key contributory factors in Parkinson's disease (PD) physiopathology. While the causes responsible for the progressive loss of midbrain dopaminergic (mDA) neuronal cell bodies in the subtantia nigra pars compacta are poorly understood, aging, genetics,...

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Detalhes bibliográficos
Publicado no:Front Aging Neurosci
Main Authors: L'Episcopo, Francesca, Tirolo, Cataldo, Serapide, Maria F., Caniglia, Salvatore, Testa, Nunzio, Leggio, Loredana, Vivarelli, Silvia, Iraci, Nunzio, Pluchino, Stefano, Marchetti, Bianca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816064/
https://ncbi.nlm.nih.gov/pubmed/29483868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00012
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