Microglia Polarization, Gene-Environment Interactions and Wnt/β-Catenin Signaling: Emerging Roles of Glia-Neuron and Glia-Stem/Neuroprogenitor Crosstalk for Dopaminergic Neurorestoration in Aged Parkinsonian Brain

Neuroinflammatory processes are recognized key contributory factors in Parkinson's disease (PD) physiopathology. While the causes responsible for the progressive loss of midbrain dopaminergic (mDA) neuronal cell bodies in the subtantia nigra pars compacta are poorly understood, aging, genetics,...

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Bibliographische Detailangaben
Veröffentlicht in:Front Aging Neurosci
Hauptverfasser: L'Episcopo, Francesca, Tirolo, Cataldo, Serapide, Maria F., Caniglia, Salvatore, Testa, Nunzio, Leggio, Loredana, Vivarelli, Silvia, Iraci, Nunzio, Pluchino, Stefano, Marchetti, Bianca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816064/
https://ncbi.nlm.nih.gov/pubmed/29483868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2018.00012
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