Early Detection of Abnormal Prion Protein in Genetic Human Prion Diseases Now Possible Using Real-Time QUIC Assay

INTRODUCTION: The definitive diagnosis of genetic prion diseases (gPrD) requires pathological confirmation. To date, diagnosis has relied upon the finding of the biomarkers 14-3-3 protein and total tau (t-tau) protein in the cerebrospinal fluid (CSF), but many researchers have reported that these ma...

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Autors principals: Sano, Kazunori, Satoh, Katsuya, Atarashi, Ryuichiro, Takashima, Hiroshi, Iwasaki, Yasushi, Yoshida, Mari, Sanjo, Nobuo, Murai, Hiroyuki, Mizusawa, Hidehiro, Schmitz, Matthias, Zerr, Inga, Kim, Yong-Sun, Nishida, Noriyuki
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556051/
https://ncbi.nlm.nih.gov/pubmed/23372790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054915
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