Effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites: exploration of a novel CYP2B6 phenotyping index

AIMS: To evaluate the effects of clopidogrel and itraconazole on the disposition of efavirenz and its hydroxyl metabolites in relation to the CYP2B6*6 genotype and explore potential phenotyping indices for CYP2B6 activity in vivo using a low dose of oral efavirenz. METHODS: We conducted a randomized...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jiang, Fen, Desta, Zeruesenay, Shon, Ji-Hong, Yeo, Chang-Woo, Kim, Ho-Sook, Liu, Kwang-Hyeon, Bae, Soo-Kyung, Lee, Sang-Seop, Flockhart, David A, Shin, Jae-Gook
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2013
Fag:
Methods in Clinical Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555064/
https://ncbi.nlm.nih.gov/pubmed/22554354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04314.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker