Developmental pharmacokinetics of propylene glycol in preterm and term neonates

AIM: Propylene glycol (PG) is often applied as an excipient in drug formulations. As these formulations may also be used in neonates, the aim of this study was to characterize the pharmacokinetics of propylene glycol, co-administered intravenously with paracetamol (800 mg PG/1000 mg paracetamol) or...

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Autori principali: De Cock, Roosmarijn F W, Knibbe, Catherijne A J, Kulo, Aida, de Hoon, Jan, Verbesselt, Rene, Danhof, Meindert, Allegaert, Karel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555055/
https://ncbi.nlm.nih.gov/pubmed/22536830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04312.x
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