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Developmental pharmacokinetics of propylene glycol in preterm and term neonates

AIM: Propylene glycol (PG) is often applied as an excipient in drug formulations. As these formulations may also be used in neonates, the aim of this study was to characterize the pharmacokinetics of propylene glycol, co-administered intravenously with paracetamol (800 mg PG/1000 mg paracetamol) or...

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Détails bibliographiques
Auteurs principaux: De Cock, Roosmarijn F W, Knibbe, Catherijne A J, Kulo, Aida, de Hoon, Jan, Verbesselt, Rene, Danhof, Meindert, Allegaert, Karel
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3555055/
https://ncbi.nlm.nih.gov/pubmed/22536830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04312.x
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