Body weight, gender and pregnancy affect enantiomer‐specific ketorolac pharmacokinetics

AIMS: Although ketorolac analgesia is linked only to the S‐enantiomer, there is limited information on the stereo‐selective pharmacokinetics of this agent. We studied the stereo‐selective pharmacokinetics of ketorolac in a pooled dataset of two studies, with women at delivery and 4–5 months postpart...

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Publicat a:Br J Clin Pharmacol
Autors principals: Välitalo, Pyry A., Kemppainen, Heidi, Kulo, Aida, Smits, Anne, van Calsteren, Kristel, Olkkola, Klaus T., de Hoon, Jan, Knibbe, Catherijne A. J., Allegaert, Karel
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555864/
https://ncbi.nlm.nih.gov/pubmed/28429492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13311
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