Enantiomer-specific ketorolac pharmacokinetics in young women, including pregnancy and postpartum period

Racemic ketorolac clearance (CL) is significantly higher at delivery, but S-ketorolac disposition determines the analgesic effects. The aim of this study was to investigate the effect of pregnancy and postpartum period on enantiomer-specific (S and R) intravenous (IV) ketorolac pharmacokinetics (PKs...

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Publicat a:Bosn J Basic Med Sci
Autors principals: Kulo, Aida, Smits, Anne, Maleškić, Sanita, van de Velde, Marc, van Calsteren, Kristel, de Hoon, Jan, Verbesselt, Rene, Deprest, Jan, Allegaert, Karel
Format: Artigo
Idioma:Inglês
Publicat: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5341779/
https://ncbi.nlm.nih.gov/pubmed/27968707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2016.1515
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