Pharmacokinetics of paracetamol and its metabolites in women at delivery and post‐partum

AIM: A recent report on intravenous (i.v.) paracetamol pharmacokinetics (PK) showed a higher total clearance in women at delivery compared with non‐pregnant women. To describe the paracetamol metabolic and elimination routes involved in this increase in clearance, we performed a population PK analys...

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Main Authors: Kulo, Aida, Peeters, Mariska Y., Allegaert, Karel, Smits, Anne, de Hoon, Jan, Verbesselt, Rene, Lewi, Liesbeth, van de Velde, Marc, Knibbe, Catherijne A. J.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
Assuntos:
Drugs in Pregnancy and Lactation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575952/
https://ncbi.nlm.nih.gov/pubmed/22845052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2012.04402.x
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