The Fidelity of Transcription: RPB1 (RPO21) MUTATIONS THAT INCREASE TRANSCRIPTIONAL SLIPPAGE IN S. CEREVISIAE

The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in the template. Transcriptional slippage can alter t...

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Main Authors: Strathern, Jeffrey, Malagon, Francisco, Irvin, Jordan, Gotte, Deanna, Shafer, Brenda, Kireeva, Maria, Lubkowska, Lucyna, Jin, Ding Jun, Kashlev, Mikhail
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2013
Ábhair:
Gene Regulation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554935/
https://ncbi.nlm.nih.gov/pubmed/23223234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429506
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