The Fidelity of Transcription: RPB1 (RPO21) MUTATIONS THAT INCREASE TRANSCRIPTIONAL SLIPPAGE IN S. CEREVISIAE

The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in the template. Transcriptional slippage can alter t...

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Bibliografiske detaljer
Main Authors: Strathern, Jeffrey, Malagon, Francisco, Irvin, Jordan, Gotte, Deanna, Shafer, Brenda, Kireeva, Maria, Lubkowska, Lucyna, Jin, Ding Jun, Kashlev, Mikhail
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2013
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554935/
https://ncbi.nlm.nih.gov/pubmed/23223234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429506
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