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The Fidelity of Transcription: RPB1 (RPO21) MUTATIONS THAT INCREASE TRANSCRIPTIONAL SLIPPAGE IN S. CEREVISIAE

The fidelity of RNA synthesis depends on both accurate template-mediated nucleotide selection and proper maintenance of register between template and RNA. Loss of register, or transcriptional slippage, is particularly likely on homopolymeric runs in the template. Transcriptional slippage can alter t...

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Detalhes bibliográficos
Main Authors: Strathern, Jeffrey, Malagon, Francisco, Irvin, Jordan, Gotte, Deanna, Shafer, Brenda, Kireeva, Maria, Lubkowska, Lucyna, Jin, Ding Jun, Kashlev, Mikhail
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554935/
https://ncbi.nlm.nih.gov/pubmed/23223234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429506
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