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Mutations in the Saccharomyces cerevisiae RPB1 Gene Conferring Hypersensitivity to 6-Azauracil

RNA polymerase II (RNAPII) in eukaryotic cells drives transcription of most messenger RNAs. RNAPII core enzyme is composed of 12 polypeptides where Rpb1 is the largest subunit. To further understand the mechanisms of RNAPII transcription, we isolated and characterized novel point mutants of RPB1 tha...

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Detalhes bibliográficos
Main Authors: Malagon, Francisco, Kireeva, Maria L., Shafer, Brenda K., Lubkowska, Lucyna, Kashlev, Mikhail, Strathern, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright © 2006 by the Genetics Society of America 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1456368/
https://ncbi.nlm.nih.gov/pubmed/16510790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.052415
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