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Elevated Mutation Rate during Meiosis in Saccharomyces cerevisiae

Mutations accumulate during all stages of growth, but only germ line mutations contribute to evolution. While meiosis contributes to evolution by reassortment of parental alleles, we show here that the process itself is inherently mutagenic. We have previously shown that the DNA synthesis associated...

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Publicat a:PLoS Genet
Autors principals: Rattray, Alison, Santoyo, Gustavo, Shafer, Brenda, Strathern, Jeffrey N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287439/
https://ncbi.nlm.nih.gov/pubmed/25569256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004910
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