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GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae

The chromosomes of many eukaryotes have regions of high GC content interspersed with regions of low GC content. In the yeast Saccharomyces cerevisiae, high-GC regions are often associated with high levels of meiotic recombination. In this study, we constructed URA3 genes that differ substantially in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kiktev, Denis A., Sheng, Ziwei, Lobachev, Kirill S., Petes, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064992/
https://ncbi.nlm.nih.gov/pubmed/29987035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807334115
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