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GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae

The chromosomes of many eukaryotes have regions of high GC content interspersed with regions of low GC content. In the yeast Saccharomyces cerevisiae, high-GC regions are often associated with high levels of meiotic recombination. In this study, we constructed URA3 genes that differ substantially in...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kiktev, Denis A., Sheng, Ziwei, Lobachev, Kirill S., Petes, Thomas D.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064992/
https://ncbi.nlm.nih.gov/pubmed/29987035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807334115
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