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GC content elevates mutation and recombination rates in the yeast Saccharomyces cerevisiae

The chromosomes of many eukaryotes have regions of high GC content interspersed with regions of low GC content. In the yeast Saccharomyces cerevisiae, high-GC regions are often associated with high levels of meiotic recombination. In this study, we constructed URA3 genes that differ substantially in...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kiktev, Denis A., Sheng, Ziwei, Lobachev, Kirill S., Petes, Thomas D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6064992/
https://ncbi.nlm.nih.gov/pubmed/29987035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807334115
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