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Elevated Mutation Rate during Meiosis in Saccharomyces cerevisiae

Mutations accumulate during all stages of growth, but only germ line mutations contribute to evolution. While meiosis contributes to evolution by reassortment of parental alleles, we show here that the process itself is inherently mutagenic. We have previously shown that the DNA synthesis associated...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Rattray, Alison, Santoyo, Gustavo, Shafer, Brenda, Strathern, Jeffrey N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287439/
https://ncbi.nlm.nih.gov/pubmed/25569256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004910
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