The Autoimmunity Risk Variant LYP-W620 Cooperates with CSK in the Regulation of TCR Signaling

The protein tyrosine phosphatase LYP, a key regulator of TCR signaling, presents a single nucleotide polymorphism, C1858T, associated with several autoimmune diseases such as type I diabetes, rheumatoid arthritis, and lupus. This polymorphism changes an R by a W in the P1 Pro rich motif of LYP, whic...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: de la Puerta, María Luisa, Trinidad, Antonio G., Rodríguez, María del Carmen, de Pereda, José María, Sánchez Crespo, Mariano, Bayón, Yolanda, Alonso, Andrés
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554717/
https://ncbi.nlm.nih.gov/pubmed/23359562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054569
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker