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High Doses of Romiplostim Induce Proliferation and Reduce Proplatelet Formation by Human Megakaryocytes

BACKGROUND: Romiplostim (AMG531) is a Thrombopoietin (TPO) receptor agonist with no homology with the endogenous TPO that has been used to treat patients affected by immune thrombocytopenia (ITP). Despite the use of TPO mimetics in the clinical practice, the mechanisms underlying their impact on meg...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Currao, Manuela, Balduini, Carlo L., Balduini, Alessandra
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554640/
https://ncbi.nlm.nih.gov/pubmed/23359807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054723
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