Abnormal proplatelet formation and emperipolesis in cultured human megakaryocytes from gray platelet syndrome patients

The Gray Platelet Syndrome (GPS) is a rare inherited bleeding disorder characterized by deficiency of platelet α-granules, macrothrombocytopenia and marrow fibrosis. The autosomal recessive form of GPS is linked to loss of function mutations in NBEAL2, which is predicted to regulate granule traffick...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Di Buduo, Christian A., Alberelli, Maria Adele, Glembostky, Ana C., Podda, Gianmarco, Lev, Paola R., Cattaneo, Marco, Landolfi, Raffaele, Heller, Paula G., Balduini, Alessandra, De Candia, Erica
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4796794/
https://ncbi.nlm.nih.gov/pubmed/26987485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep23213
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