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Single-Cell Analysis of Ribonucleotide Reductase Transcriptional and Translational Response to DNA Damage

The ribonucleotide reductase (RNR) enzyme catalyzes an essential step in the production of deoxyribonucleotide triphosphates (dNTPs) in cells. Bulk biochemical measurements in synchronized Saccharomyces cerevisiae cells suggest that RNR mRNA production is maximal in late G(1) and S phases; however,...

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Bibliografische gegevens
Hoofdauteurs: Mazumder, Aprotim, Tummler, Katja, Bathe, Mark, Samson, Leona D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554213/
https://ncbi.nlm.nih.gov/pubmed/23184665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01020-12
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