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Single-Cell Analysis of Ribonucleotide Reductase Transcriptional and Translational Response to DNA Damage
The ribonucleotide reductase (RNR) enzyme catalyzes an essential step in the production of deoxyribonucleotide triphosphates (dNTPs) in cells. Bulk biochemical measurements in synchronized Saccharomyces cerevisiae cells suggest that RNR mRNA production is maximal in late G(1) and S phases; however,...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3554213/ https://ncbi.nlm.nih.gov/pubmed/23184665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01020-12 |
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