Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

An effective response to DNA damaging agents involves modulating numerous facets of cellular homeostasis in addition to DNA repair and cell-cycle checkpoint pathways. Fluorescence microscopy-based imaging offers the opportunity to simultaneously interrogate changes in both protein level and subcellu...

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Main Authors: Mazumder, Aprotim, Pesudo, Laia Quiros, McRee, Siobhan, Bathe, Mark, Samson, Leona D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Genome Integrity, Repair and Replication
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814357/
https://ncbi.nlm.nih.gov/pubmed/23935119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt715
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