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Genome-wide single-cell-level screen for protein abundance and localization changes in response to DNA damage in S. cerevisiae

An effective response to DNA damaging agents involves modulating numerous facets of cellular homeostasis in addition to DNA repair and cell-cycle checkpoint pathways. Fluorescence microscopy-based imaging offers the opportunity to simultaneously interrogate changes in both protein level and subcellu...

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Autors principals: Mazumder, Aprotim, Pesudo, Laia Quiros, McRee, Siobhan, Bathe, Mark, Samson, Leona D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814357/
https://ncbi.nlm.nih.gov/pubmed/23935119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt715
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