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Single-Cell Analysis of Ribonucleotide Reductase Transcriptional and Translational Response to DNA Damage

The ribonucleotide reductase (RNR) enzyme catalyzes an essential step in the production of deoxyribonucleotide triphosphates (dNTPs) in cells. Bulk biochemical measurements in synchronized Saccharomyces cerevisiae cells suggest that RNR mRNA production is maximal in late G(1) and S phases; however,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mazumder, Aprotim, Tummler, Katja, Bathe, Mark, Samson, Leona D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554213/
https://ncbi.nlm.nih.gov/pubmed/23184665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01020-12
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